Dramatic Improvement of CRISPR/Cas9 Editing in <named-content content-type="genus-species">Candida albicans</named-content> by Increased Single Guide RNA Expression
ABSTRACT The clustered regularly interspaced short palindromic repeat system with CRISPR-associated protein 9 nuclease (CRISPR/Cas9) has emerged as a versatile tool for genome editing in Candida albicans. Mounting evidence from other model systems suggests that the intracellular levels of single gui...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-04-01
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Series: | mSphere |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mSphere.00385-16 |