Leptin Receptor Deficiency Results in Hyperphagia and Increased Fatty Acid Mobilization during Fasting in Rainbow Trout (<i>Oncorhynchus mykiss</i>)
Leptin is a pleiotropic hormone known for regulating appetite and metabolism. To characterize the role of leptin signaling in rainbow trout, we used CRISPR/Cas9 genome editing to disrupt the leptin receptor (LepR) genes, <i>lepra1</i> and <i>lepra2</i>. We compared wildtype (...
| Auteurs principaux: | , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
MDPI AG
2022-03-01
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| Collection: | Biomolecules |
| Sujets: | |
| Accès en ligne: | https://www.mdpi.com/2218-273X/12/4/516 |