Power analysis for RNA-Seq differential expression studies

Power analysis for RNA-Seq differential expression studies

Abstract Background Sample size calculation and power estimation are essential components of experimental designs in biomedical research. It is very challenging to estimate power for RNA-Seq differential expression under complex experimental designs. Moreover, the dependency among genes should be ta...

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Bibliographic Details
Main Authors: Lianbo Yu, Soledad Fernandez, Guy Brock
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Bioinformatics
Subjects:
RNA-Seq
Power
Wald test
Likelihood ratio test
Online Access:http://link.springer.com/article/10.1186/s12859-017-1648-2

Internet

http://link.springer.com/article/10.1186/s12859-017-1648-2

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