Red Blood Cell Metabolism in Pyruvate Kinase Deficient Patients
Background: Pyruvate kinase deficiency (PKD) is the most frequent congenital enzymatic defect of glycolysis, and one of the most common causes of hereditary non spherocytic hemolytic anemia. Therapeutic interventions are limited, in part because of the incomplete understanding of the molecular mecha...
Main Authors: | Micaela K. Roy, Francesca Cendali, Gabrielle Ooyama, Fabia Gamboni, Holmes Morton, Angelo D’Alessandro |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-10-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.735543/full |
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