Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.

The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus neutralization profile with a non-sigmoidal slope and a plateau at <100% neutralization. In the current study, we were interested in determini...

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Bibliographic Details
Main Authors: Laura E McCoy, Emilia Falkowska, Katie J Doores, Khoa Le, Devin Sok, Marit J van Gils, Zelda Euler, Judith A Burger, Michael S Seaman, Rogier W Sanders, Hanneke Schuitemaker, Pascal Poignard, Terri Wrin, Dennis R Burton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4534392?pdf=render

Internet

http://europepmc.org/articles/PMC4534392?pdf=render

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