Induction of Neutralizing Responses against Autologous Virus in Maternal HIV Vaccine Trials

Induction of Neutralizing Responses against Autologous Virus in Maternal HIV Vaccine Trials

ABSTRACT A maternal vaccine capable of boosting neutralizing antibody (NAb) responses directed against circulating viruses in HIV-infected pregnant women could effectively decrease mother-to-child transmission of HIV. However, it is not known if an HIV envelope (Env) vaccine administered to infected...

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Bibliographic Details
Main Authors: Eliza D. Hompe, Jesse F. Mangold, Amit Kumar, Joshua A. Eudailey, Erin McGuire, Barton F. Haynes, M. Anthony Moody, Peter F. Wright, Genevieve G. Fouda, Elena E. Giorgi, Feng Gao, Sallie R. Permar
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mSphere
Subjects:
HIV envelope
autologous virus neutralization
human immunodeficiency virus
maternal vaccination
mother-to-child transmission
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00254-20

Internet

https://journals.asm.org/doi/10.1128/mSphere.00254-20

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