Defective mitophagy and the etiopathogenesis of Alzheimer’s disease

Abstract Accumulation of impaired mitochondria and energy metabolism disorders are non-negligible features of both aging and age-related neurodegeneration, including Alzheimer’s disease (AD). A growing number of studies suggest that mitophagy disorders play an important role in AD occurrence and dev...

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Bibliographic Details
Main Authors: Kuan Zeng, Xuan Yu, Yacoubou Abdoul Razak Mahaman, Jian-Zhi Wang, Rong Liu, Yi Li, Xiaochuan Wang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Translational Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s40035-022-00305-1