Genetic study of the hepcidin gene (<it>HAMP</it>) promoter and functional analysis of the c.-582A > G variant
<p>Abstract</p> <p>Background</p> <p>Hepcidin acts as the main regulator of iron homeostasis through regulation of intestinal absorption and macrophage release. Hepcidin deficiency causes iron overload whereas its overproduction is associated with anaemia of chronic dis...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-12-01
|
Series: | BMC Genetics |
Online Access: | http://www.biomedcentral.com/1471-2156/11/110 |