Genetic study of the hepcidin gene (<it>HAMP</it>) promoter and functional analysis of the c.-582A > G variant

<p>Abstract</p> <p>Background</p> <p>Hepcidin acts as the main regulator of iron homeostasis through regulation of intestinal absorption and macrophage release. Hepcidin deficiency causes iron overload whereas its overproduction is associated with anaemia of chronic dis...

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Detalles Bibliográficos
Autores principales: Domínguez Fernando, Quinteiro Celsa, Campos Joaquín, González-Quintela Arturo, Parajes Silvia, Loidi Lourdes
Formato: Artículo
Lenguaje:English
Publicado: BMC 2010-12-01
Colección:BMC Genetics
Acceso en línea:http://www.biomedcentral.com/1471-2156/11/110