Genetic study of the hepcidin gene (<it>HAMP</it>) promoter and functional analysis of the c.-582A > G variant

<p>Abstract</p> <p>Background</p> <p>Hepcidin acts as the main regulator of iron homeostasis through regulation of intestinal absorption and macrophage release. Hepcidin deficiency causes iron overload whereas its overproduction is associated with anaemia of chronic dis...

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Bibliographic Details
Main Authors: Domínguez Fernando, Quinteiro Celsa, Campos Joaquín, González-Quintela Arturo, Parajes Silvia, Loidi Lourdes
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/11/110