A case report of anti-GAD65 antibody-positive autoimmune encephalitis in children associated with autoimmune polyendocrine syndrome type-II and literature review

A case report of anti-GAD65 antibody-positive autoimmune encephalitis in children associated with autoimmune polyendocrine syndrome type-II and literature review

BackgroundGlutamic acid decarboxylase (GAD) is the rate-limiting enzyme for the synthesis of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Antibodies against glutamic acid decarboxylase (GAD) are associated with various neurologic conditions des...

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Bibliographic Details
Main Authors: Tamang Sapana, Wei Li, Fengyan Tian, Wenhao Yan, Binghua Dou, Shuang Hua, Zhihong Zhuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
anti GAD65 antibody
T1DM (type 1 diabetes mellitus)
autoimmune thyroiditis
pediatric
autoimmune polyendocrine syndrome (APS type 2)
abnormal (behavior)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1274672/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1274672/full

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