Toward robust N-glycomics of various tissue samples that may contain glycans with unknown or unexpected structures

Abstract Glycans in tissues are structurally diverse and usually include a large number of isomers that cannot be easily distinguished by mass spectrometry (MS). To address this issue, we developed a combined method that can efficiently separate and identify glycan isomers. First, we separated 2-ami...

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Bibliographic Details
Main Authors: Noriko Suzuki, Tatsuya Abe, Ken Hanzawa, Shunji Natsuka
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84668-x