Establishment and Optimization of Radiomics Algorithms for Prediction of KRAS Gene Mutation by Integration of NSCLC Gene Mutation Mutual Exclusion Information

Establishment and Optimization of Radiomics Algorithms for Prediction of KRAS Gene Mutation by Integration of NSCLC Gene Mutation Mutual Exclusion Information

Purpose: To assess the significance of mutation mutual exclusion information in the optimization of radiomics algorithms for predicting gene mutation.Methods: We retrospectively analyzed 258 non-small cell lung cancer (NSCLC) patients. Patients were randomly divided into training (n = 180) and valid...

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Bibliographic Details
Main Authors: Jingyi Wang, Xing Lv, Weicheng Huang, Zhiyong Quan, Guiyu Li, Shuo Wu, Yirong Wang, Zhaojuan Xie, Yuhao Yan, Xiang Li, Wenhui Ma, Weidong Yang, Xin Cao, Fei Kang, Jing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
non-small cell lung cancer
EGFR
KRAS
PET/CT
radiomics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.862581/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.862581/full

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