CELF1 promotes matrix metalloproteinases gene expression at transcriptional level in lens epithelial cells

CELF1 promotes matrix metalloproteinases gene expression at transcriptional level in lens epithelial cells

Abstract Background RNA binding proteins (RBPs)-mediated regulation plays important roles in many eye diseases, including the canonical RBP CELF1 in cataract. While the definite molecular regulatory mechanisms of CELF1 on cataract still remain elusive. Methods In this study, we overexpressed CELF1 i...

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Bibliographic Details
Main Authors: Jun Xiao, Xin Tian, Siyan Jin, Yanhui He, Meijiao Song, He Zou
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Ophthalmology
Subjects:
CELF1
Transcriptional regulation
RNA-seq
MMPs
Cataract
Online Access:https://doi.org/10.1186/s12886-022-02344-8

Internet

https://doi.org/10.1186/s12886-022-02344-8

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