Genetic Susceptibility to Antisynthetase Syndrome Associated With Single-Nucleotide Variants in the IL1B Gene That Lead Variation in IL-1β Serum Levels

Genetic Susceptibility to Antisynthetase Syndrome Associated With Single-Nucleotide Variants in the IL1B Gene That Lead Variation in IL-1β Serum Levels

The antisynthetase syndrome (ASSD) is an autoimmune disorder characterized by myositis, arthritis, mechanic's hands, fever, Raynaud phenomenon, and interstitial lung disease (ILD). We aimed to evaluate single-nucleotide polymorphisms in the interleukin 1B (IL1B) gene and their association betwe...

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Bibliographic Details
Main Authors: Marco Antonio Ponce-Gallegos, Espiridión Ramos-Martínez, Adriana García-Carmona, Mayra Mejía, Karol J. Nava-Quiroz, Gloria Pérez-Rubio, Enrique Ambrocio-Ortiz, Montserrat I. González-Pérez, Ivette Buendía-Roldán, Jorge Rojas-Serrano, Ramcés Falfán-Valencia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Medicine
Subjects:
antisynthetase syndrome
IL1B gene
IL1-beta
SNP
anti-Jo1
genetic association
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.547186/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.547186/full

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