Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)
The design, synthesis and antibiotic activities of the modified carboxylate binding pocket (D-O-E ring) of vancomycin (1) are summarized in this short account. The preliminary structure–activity relationship (SAR) studies indicated that both the structure of the 16-membered macrocycle incl...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
2013-12-01
|
| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://www.chimia.ch/chimia/article/view/5494 |