Impact of human sepsis on CCCTC-binding factor associated monocyte transcriptional response of Major Histocompatibility Complex II components.

Impact of human sepsis on CCCTC-binding factor associated monocyte transcriptional response of Major Histocompatibility Complex II components.

BACKGROUND:Antigen presentation on monocyte surface to T-cells by Major Histocompatibility Complex, Class II (MHC-II) molecules is fundamental for pathogen recognition and efficient host response. Accordingly, loss of Major Histocompatibility Complex, Class II, DR (HLA-DR) surface expression indicat...

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Bibliographic Details
Main Authors: Benedikt Hermann Siegler, Florian Uhle, Christoph Lichtenstern, Christoph Arens, Marek Bartkuhn, Markus Alexander Weigand, Sebastian Weiterer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6136812?pdf=render

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http://europepmc.org/articles/PMC6136812?pdf=render

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