Developing an Agent-Based Drug Model to Investigate the Synergistic Effects of Drug Combinations

Developing an Agent-Based Drug Model to Investigate the Synergistic Effects of Drug Combinations

The growth and survival of cancer cells are greatly related to their surrounding microenvironment. To understand the regulation under the impact of anti-cancer drugs and their synergistic effects, we have developed a multiscale agent-based model that can investigate the synergistic effects of drug c...

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Bibliographic Details
Main Authors: Hongjie Gao, Zuojing Yin, Zhiwei Cao, Le Zhang
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
agent-based model
parameter estimation
synergistic effect
drug combination
optimization
Online Access:https://www.mdpi.com/1420-3049/22/12/2209

Internet

https://www.mdpi.com/1420-3049/22/12/2209

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