Factor Xa and thrombin induce endothelial progenitor cell activation. The effect of direct oral anticoagulants

Factor Xa (FXa) and thrombin exert non-hemostatic cellular actions primarily mediated through protease-activated receptors (PARs). We investigated the effect of FXa and thrombin on human late-outgrowth endothelial cells (OECs), a type of endothelial progenitor cells (EPCs), and on human umbilical ve...

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Bibliographic Details
Main Authors: Styliani Papadaki, Sofia Sidiropoulou, Iraklis C. Moschonas, Alexandros D. Tselepis
Format: Article
Language:English
Published: Taylor & Francis Group 2021-08-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2020.1802413