Factor Xa and thrombin induce endothelial progenitor cell activation. The effect of direct oral anticoagulants

Factor Xa and thrombin induce endothelial progenitor cell activation. The effect of direct oral anticoagulants

Factor Xa (FXa) and thrombin exert non-hemostatic cellular actions primarily mediated through protease-activated receptors (PARs). We investigated the effect of FXa and thrombin on human late-outgrowth endothelial cells (OECs), a type of endothelial progenitor cells (EPCs), and on human umbilical ve...

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Bibliographic Details
Main Authors: Styliani Papadaki, Sofia Sidiropoulou, Iraklis C. Moschonas, Alexandros D. Tselepis
Format: Article
Language:English
Published: Taylor & Francis Group 2021-08-01
Series:Platelets
Subjects:
dabigatran
endothelial progenitor cells
factor xa
rivaroxaban
thrombin
vorapaxar
Online Access:http://dx.doi.org/10.1080/09537104.2020.1802413

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