Characterization and modulation of the pro‐inflammatory effects of immune cells in the canine intervertebral disk

Characterization and modulation of the pro‐inflammatory effects of immune cells in the canine intervertebral disk

Abstract Background Intervertebral disk (IVD) degeneration affects both humans and canines and is a major cause of low back pain (LBP). Mast cell (MC) and macrophage (MØ) infiltration has been identified in the pathogenesis of IVD degeneration (IVDD) in the human and rodent model but remains underst...

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Bibliographic Details
Main Authors: Mary K. Heimann, Kelly Thompson, Gilian Gunsch, Shirley N. Tang, Brett Klamer, Kara Corps, Benjamin A. Walter, Sarah A. Moore, Devina Purmessur
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:JOR Spine
Subjects:
canine
cromolyn sodium
degeneration
intervertebral disk
low back pain
macrophage
Online Access:https://doi.org/10.1002/jsp2.1333

Internet

https://doi.org/10.1002/jsp2.1333

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