The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1.

The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1.

Genome wide association studies (GWAS) have identified thousands of single nucleotide polymorphisms (SNPs) associated with the risk of common disorders. However, since the large majority of these risk SNPs reside outside gene-coding regions, GWAS generally provide no information about causal mechani...

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Main Authors: Lijiang Ma, Nicole S Bryce, Adam W Turner, Antonio F Di Narzo, Karishma Rahman, Yang Xu, Raili Ermel, Katyayani Sukhavasi, Valentina d'Escamard, Nirupama Chandel, Bhargavi V'Gangula, Kathryn Wolhuter, Daniella Kadian-Dodov, Oscar Franzen, Arno Ruusalepp, Ke Hao, Clint L Miller, Johan L M Björkegren, Jason C Kovacic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010261

Internet

https://doi.org/10.1371/journal.pgen.1010261

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