Virion Secretion of Hepatitis B Virus Naturally Occurring Core Antigen Variants

In natural infection, hepatitis B virus (HBV) core protein (HBc) accumulates frequent mutations. The most frequent HBc variant in chronic hepatitis B patients is mutant 97L, changing from an isoleucine or phenylalanine to a leucine (L) at HBc amino acid 97. One dogma in the HBV research field is tha...

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Bibliographic Details
Main Authors: Chiaho Shih, Szu-Yao Wu, Shu-Fan Chou, Ta-Tung Thomas Yuan
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/1/43