Piezoelectric Microvibration Mitigates Estrogen Loss-Induced Osteoporosis and Promotes Piezo1, MicroRNA-29a, and Wnt3a Signaling in Osteoblasts

Piezoelectric Microvibration Mitigates Estrogen Loss-Induced Osteoporosis and Promotes Piezo1, MicroRNA-29a, and Wnt3a Signaling in Osteoblasts

Biophysical stimulation alters bone-forming cell activity, bone formation and remodeling. The effect of piezoelectric microvibration stimulation (PMVS) intervention on osteoporosis development remains uncertain. We investigated whether 60 Hz, 120 Hz, and 180 Hz PMVS (0.05 g, 20 min/stimulation, 3 st...

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Bibliographic Details
Main Authors: Re-Wen Wu, Wei-Shiung Lian, Yu-Shan Chen, Jih-Yang Ko, Shao-Yu Wang, Holger Jahr, Feng-Sheng Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
piezoelectric microvibration
osteoporosis
Piezo1
Wnt3a
Dkk1
microRNA-29a
Online Access:https://www.mdpi.com/1422-0067/22/17/9476

Internet

https://www.mdpi.com/1422-0067/22/17/9476

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