Identification of Novel Biomarkers for Drug Hypersensitivity After Sequencing of the Promoter Area in 16 Genes of the Vitamin D Pathway and the High-Affinity IgE Receptor

Identification of Novel Biomarkers for Drug Hypersensitivity After Sequencing of the Promoter Area in 16 Genes of the Vitamin D Pathway and the High-Affinity IgE Receptor

The prevalence of allergic diseases and drug hypersensitivity reactions (DHRs) during recent years is increasing. Both, allergic diseases and DHRs seem to be related to an interplay between environmental factors and genetic susceptibility. In recent years, a large effort in the elucidation of the ge...

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Bibliographic Details
Main Authors: Gemma Amo, Manuel Martí, Jesús M. García-Menaya, Concepción Cordobés, José A. Cornejo-García, Natalia Blanca-López, Gabriela Canto, Inmaculada Doña, Miguel Blanca, María José Torres, José A. G. Agúndez, Elena García-Martín
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Genetics
Subjects:
Next-Generation Sequencing (NGS)
vitamin D
high-affinity IgE receptor (FCεRI)
NSAIDs (non-steroidal anti-inflammatory drugs)
beta-lactam antibiotic
drugs hypersensitivity reactions
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00582/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00582/full

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