HIV-1 active and latent infections induce disparate chromatin reorganization and transcriptional regulation of mRNAs and lncRNAs in SupT1 cells

HIV-1 active and latent infections induce disparate chromatin reorganization and transcriptional regulation of mRNAs and lncRNAs in SupT1 cells

ABSTRACTHIV-1 latency is a multi-dimensional, dynamic process, and many aspects of how the viral latency is established and maintained remain incompletely characterized. We have investigated how the host cellular epigenomic and transcriptomic microenvironments compare depending on the transcriptiona...

Full description

Bibliographic Details
Main Authors: Gabrielle Lê-Bury, Yao Chen, Jordan M. Rhen, Jennifer K. Grenier, Amit Singhal, David G. Russell, Saikat Boliar
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
HIV-1
latency
epigenome
transcriptome
lncRNA
Online Access:https://journals.asm.org/doi/10.1128/mbio.02619-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02619-23

Similar Items