The estrogen response in fibroblasts promotes ovarian metastases of gastric cancer

The estrogen response in fibroblasts promotes ovarian metastases of gastric cancer

Abstract Younger premenopausal women are more prone to developing ovarian metastases (OM) of gastric cancer (GC) than metastases of other organs; however, the molecular mechanisms remain unclear. Here we perform single-cell RNA sequencing on 45 tumor samples from 18 GC patients with OM. Interestingl...

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Bibliographic Details
Main Authors: Simeng Hu, Can Hu, Jingli Xu, Pengfei Yu, Li Yuan, Ziyu Li, Haohong Liang, Yanqiang Zhang, Jiahui Chen, Qing Wei, Shengjie Zhang, Litao Yang, Dan Su, Yian Du, Zhiyuan Xu, Fan Bai, Xiangdong Cheng
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-52615-9

Internet

https://doi.org/10.1038/s41467-024-52615-9

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