MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study

MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study

Abstract Background Extranodal extension (ENE) is an adverse prognostic factor for oral squamous cell carcinoma (OSCC), and patients with OSCC along with ENE require neck dissection. In this study, we developed a novel ENE histology-based pathological predictor using MMP14 expression patterns in sma...

Full description

Bibliographic Details
Main Authors: Yuri Noda, Mitsuaki Ishida, Ryosuke Yamaka, Yasuhiro Ueno, Tomofumi Sakagami, Takuo Fujisawa, Hiroshi Iwai, Koji Tsuta
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Cancer
Subjects:
Extranodal extension
Oral squamous cell carcinoma
Matrix metalloproteinase 14
Membrane-type 1 matrix metalloproteinase
Cancer-associated fibroblast
Predictor
Online Access:https://doi.org/10.1186/s12885-023-10595-x

Internet

https://doi.org/10.1186/s12885-023-10595-x

Similar Items