A review of family-based tests for linkage disequilibrium between a quantitative trait and a genetic marker.

Quantitative trait transmission/disequilibrium tests (quantitative TDTs) are commonly used in family-based genetic association studies of quantitative traits. Despite the availability of various quantitative TDTs, some users are not aware of the properties of these tests and the relationships betwee...

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Bibliographic Details
Main Authors: Warren J Ewens, Mingyao Li, Richard S Spielman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2528965?pdf=render