Cadmium exposure reprograms energy metabolism of hematopoietic stem cells to promote myelopoiesis at the expense of lymphopoiesis in mice

Cadmium exposure reprograms energy metabolism of hematopoietic stem cells to promote myelopoiesis at the expense of lymphopoiesis in mice

Cadmium (Cd) is a highly toxic heavy metal in our living environment. Hematopoietic stem cells (HSC) are ancestors for all blood cells. Therefore understanding the impact of Cd on HSC is significant for public health. The aim of this study was to investigate the impact of Cd2+ on energy metabolism o...

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Bibliographic Details
Main Authors: Yifan Zhao, Jinyi He, Tingting Zhu, Yufan Zhang, Yue Zhai, Peng Xue, Ye Yao, Zhijun Zhou, Miao He, Weidong Qu, Yubin Zhang
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
Hematopoietic stem cells
Energy metabolism
Glycolysis
Mitochondrial oxidative phosphorylation
Myelopoiesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322000483

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http://www.sciencedirect.com/science/article/pii/S0147651322000483

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