A profile of brain reserve in adults at genetic risk of Alzheimer's disease

Abstract Introduction The apolipoprotein E (APOE) ε4 allele is the greatest genetic risk factor for Alzheimer's disease (AD). Our aim was to identify the structural brain measures that mitigate the negative effect of APOE ε4 on cognition, which would have implications for AD diagnosis and treat...

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Bibliographic Details
Main Authors: Gillian Coughlan, Peter Zhukovsky, Aristotle Voineskos, Cheryl Grady
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Online Access:https://doi.org/10.1002/dad2.12208