TDP-43 upregulates lipid metabolism modulator ABHD2 to suppress apoptosis in hepatocellular carcinoma
TDP-43 acts as an RNA-binding protein that regulates the RNA stability of ABHD2 and affects the release of fatty acids and ROS, which in turn regulates apoptosis and affects the growth of liver tumors.
| Hauptverfasser: | , , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Nature Portfolio
2022-08-01
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| Schriftenreihe: | Communications Biology |
| Online Zugang: | https://doi.org/10.1038/s42003-022-03788-w |