TDP-43 upregulates lipid metabolism modulator ABHD2 to suppress apoptosis in hepatocellular carcinoma
TDP-43 acts as an RNA-binding protein that regulates the RNA stability of ABHD2 and affects the release of fatty acids and ROS, which in turn regulates apoptosis and affects the growth of liver tumors.
| المؤلفون الرئيسيون: | , , , , , , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
Nature Portfolio
2022-08-01
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| سلاسل: | Communications Biology |
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s42003-022-03788-w |