Caf1 regulates the histone methyltransferase activity of Ash1 by sensing unmodified histone H3
Abstract Histone modifications are one of the many key mechanisms that regulate gene expression. Ash1 is a histone H3K36 methyltransferase and is involved in gene activation. Ash1 forms a large complex with Mrg15 and Caf1/p55/Nurf55/RbAp48 (AMC complex). The Ash1 subunit alone exhibits very low acti...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-04-01
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| Series: | Epigenetics & Chromatin |
| Online Access: | https://doi.org/10.1186/s13072-023-00487-6 |