Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms

Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms

The wild-type protein p53 plays a key role in preventing the formation of neoplasms by controlling cell growth. However, in more than a half of all cancers, the <i>TP53</i> gene has missense mutations that appear during tumorigenesis. In most cases, the mutated gene encodes a full-length...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Elena Butturini, Giovanna Butera, Raffaella Pacchiana, Alessandra Carcereri de Prati, Sofia Mariotto, Massimo Donadelli
Format: Artykuł
Język:English
Wydane: MDPI AG 2021-11-01
Seria:Cells
Hasła przedmiotowe:
cancer
p53
mutant p53
redox
oxidative stress
post-translational modifications
Dostęp online:https://www.mdpi.com/2073-4409/10/11/3149

Internet

https://www.mdpi.com/2073-4409/10/11/3149

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