Homologated amino acids with three vicinal fluorines positioned along the backbone: development of a stereoselective synthesis

Backbone-extended amino acids have a variety of potential applications in peptide and protein science, particularly if the geometry of the amino acid is controllable. Here we describe the synthesis of δ-amino acids that contain three vicinal C–F bonds positioned along the backbone. The ultimately su...

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Bibliographic Details
Main Authors: Raju Cheerlavancha, Ahmed Ahmed, Yun Cheuk Leung, Aggie Lawer, Qing-Quan Liu, Marina Cagnes, Hee-Chan Jang, Xiang-Guo Hu, Luke Hunter
Format: Article
Language:English
Published: Beilstein-Institut 2017-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.13.228