Homologated amino acids with three vicinal fluorines positioned along the backbone: development of a stereoselective synthesis
Backbone-extended amino acids have a variety of potential applications in peptide and protein science, particularly if the geometry of the amino acid is controllable. Here we describe the synthesis of δ-amino acids that contain three vicinal C–F bonds positioned along the backbone. The ultimately su...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2017-11-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.13.228 |