Assigning the Absolute Configurations of Chiral Primary Amines Based on Experimental and DFT-Calculated 19F Nuclear Magnetic Resonance

Assigning the Absolute Configurations of Chiral Primary Amines Based on Experimental and DFT-Calculated 19F Nuclear Magnetic Resonance

In this work, a novel method for assigning the absolute configuration of a chiral primary amine has been developed based on the experimental and DFT-calculated 19F NMR chemical shift differences of its derived two fluorinated amides by reacting with two enantiomers of a chiral derivatizing agent FPP...

Full description

Bibliographic Details
Main Authors: Shiwei Yang, Guangling Bian, Rongjian Sa, Ling Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Chemistry
Subjects:
absolute configuration assignment
primary amine
19F nuclear magnetic resonance
DFT calculation
fluorinated phenylacetic phenylselenoester
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00318/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2019.00318/full

Similar Items