Super enhancers targeting ZBTB16 in osteogenesis protect against osteoporosis

Abstract As the major cell precursors in osteogenesis, mesenchymal stem cells (MSCs) are indispensable for bone homeostasis and development. However, the primary mechanisms regulating osteogenic differentiation are controversial. Composed of multiple constituent enhancers, super enhancers (SEs) are...

Full description

Bibliographic Details
Main Authors: Wenhui Yu, Zhongyu Xie, Jinteng Li, Jiajie Lin, Zepeng Su, Yunshu Che, Feng Ye, Zhaoqiang Zhang, Peitao Xu, Yipeng Zeng, Xiaojun Xu, Zhikun Li, Pei Feng, Rujia Mi, Yanfeng Wu, Huiyong Shen
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-023-00267-8