Prediction of sepsis-related outcomes in neonates through systematic genotyping of polymorphisms in genes for innate immunity and inflammation: a narrative review and critical perspective

Prediction of sepsis-related outcomes in neonates through systematic genotyping of polymorphisms in genes for innate immunity and inflammation: a narrative review and critical perspective

CONTEXT AND OBJECTIVE: Neonatal sepsis is associated with premature birth and maternal infection. Large-scale studies seek to define markers that identify neonates at risk of developing sepsis. Here, we examine whether the scientific evidence supports systematic use of polymorphism genotyping in cy...

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Bibliographic Details
Main Authors: Juliana Kilesse Carvalho, Daniella Batalha Moore, Ricardo Alves Luz, Pedro Paulo Xavier-Elsas, Maria Ignez Capella Gaspar-Elsas
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
Neonatology
Sepsis
Cytokines
Genetic predisposition to disease
Polymorphism, genetic
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802013000500338&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802013000500338&lng=en&tlng=en

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