Frequent occurrence of highly expanded but unrelated B-cell clones in patients with multiple myeloma.

Clonal diversity in multiple myeloma (MM) includes both MM-related and MM-unrelated clonal expansions which are subject to dominance exerted by the MM clone. Here we show evidence for the existence of minor but highly expanded unrelated B-cell clones in patients with MM defined by their complementar...

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Bibliographic Details
Main Authors: Jitra Kriangkum, Sarah N Motz, Carina S Debes Marun, Sandrine T Lafarge, Spencer B Gibson, Christopher P Venner, James B Johnston, Andrew R Belch, Linda M Pilarski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3665682?pdf=render