Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection

Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection

Abstract Insulin-like growth factor I (IGF-1) is a neurotrophic factor and is the ligand for insulin-like growth factor 1 receptor (IGF-1R). Reduced expression of IGF-1 has been reported to cause deafness, mental retardation, postnatal growth failure, and microcephaly. IGF-1R is expressed in the ret...

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Bibliographic Details
Main Authors: Ammaji Rajala, Kenneth Teel, Mohd A. Bhat, Albert Batushansky, Timothy M. Griffin, Lindsey Purcell, Raju V. S. Rajala
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05074-3

Internet

https://doi.org/10.1038/s41419-022-05074-3

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