PCV2 Triggers PK-15 Cell Apoptosis Through the PLC–IP3R–Ca2+ Signaling Pathway

PCV2 Triggers PK-15 Cell Apoptosis Through the PLC–IP3R–Ca2+ Signaling Pathway

The endoplasmic reticulum (ER) plays an essential role in Ca2+ concentration balance and protein biosynthesis. During infection, the virus needs to complete its life process with the help of ER. At the same time, ER also produces ER stress (ERS), which induces apoptosis to resist virus infection. Ou...

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Bibliographic Details
Main Authors: Shuo Wang, Chen Li, Panpan Sun, Jianli Shi, Xiaoyan Wu, Chang Liu, Zhe Peng, Hong Han, Shaojian Xu, Ying Yang, Yao Tian, Jiaxin Li, Hongbin He, Jun Li, Zhao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
apoptosis
porcine circovirus 2
PLC
IP3R
Cacpsdummy2+
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.674907/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.674907/full

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