Profiling the antibody response of humans protected by immunization with Plasmodium vivax radiation-attenuated sporozoites

Abstract Malaria sterile immunity has been reproducibly induced by immunization with Plasmodium radiation-attenuated sporozoites (RAS). Analyses of sera from RAS-immunized individuals allowed the identification of P. falciparum antigens, such as the circumsporozoite protein (CSP), the basis for the...

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Bibliographic Details
Main Authors: Mary Lopez-Perez, Aarti Jain, D. Huw Davies, Juan M. Vásquez-Jiménez, Sonia M. Herrera, José Oñate, Philip L. Felgner, Sócrates Herrera, Myriam Arévalo-Herrera
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-53175-0