Disparate selection of mutations in the dihydrofolate reductase gene (dhfr) of Plasmodium ovale curtisi and P. o. wallikeri in Africa.

Disparate selection of mutations in the dihydrofolate reductase gene (dhfr) of Plasmodium ovale curtisi and P. o. wallikeri in Africa.

Plasmodium ovale curtisi and P. ovale wallikeri are both endemic in sub-Saharan Africa, the Middle East and Southeast Asia. Molecular surveillance data for drug resistance in P. ovale spp. is limited at present. We analysed polymorphisms in the podhfr, pocrt and pocytb genes of P. ovale spp. in 147...

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Bibliographic Details
Main Authors: Jing Chen, Xiaoqin Ma, Jianxia Tang, Sui Xu, Yaping Gu, Feng Tang, Yuanyuan Cao, Weiming Wang, Huayun Zhou, Jiayao Zhang, Xinyu Yu, Guoding Zhu, Meng Zhu, Qingfeng Zhang, Richard Culleton, Yaobao Liu, Jun Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010977

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https://doi.org/10.1371/journal.pntd.0010977

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