CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype

CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype

Abstract Obesity is associated with chronic low-grade inflammation, contributing to an increasing prevalence of chronic metabolic diseases, such as insulin resistance, non-alcoholic fatty liver disease (NALFD), and steatohepatitis. Macrophages are the predominant immune cells in adipose tissues. Adi...

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Bibliographic Details
Main Authors: Jingchang Ma, Wei Hu, Dongliang Zhang, Jiangang Xie, Chujun Duan, Yitian Liu, Yuling Wang, Xuexue Xu, Kun Cheng, Boquan Jin, Yuan Zhang, Ran Zhuang
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Translational Medicine
Subjects:
CD226
HFD
Obesity
Macrophage
Polarization
Online Access:https://doi.org/10.1186/s12967-021-03150-4

Internet

https://doi.org/10.1186/s12967-021-03150-4

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