Functional and Expressional Analyses Reveal the Distinct Role of Complement Factor I in Regulating Complement System Activation during GCRV Infection in <i>Ctenopharyngodon idella</i>

Functional and Expressional Analyses Reveal the Distinct Role of Complement Factor I in Regulating Complement System Activation during GCRV Infection in <i>Ctenopharyngodon idella</i>

Complement factor I (CFI), a complement inhibitor, is well known for regulating the complement system activation by degrading complement component 3b (C3b) in animal serum, thus becoming involved in innate defense. Nevertheless, the functional mechanisms of CFI in the complement system and in host-p...

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Bibliographic Details
Main Authors: Yi Liu, Zhao Lv, Tiaoyi Xiao, Xuewen Zhang, Chunhua Ding, Beibei Qin, Baohong Xu, Qiaolin Liu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
grass carp
complement factor I
complement component 3b
grass carp reovirus infection
complement regulation mechanism
Online Access:https://www.mdpi.com/1422-0067/23/19/11369

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https://www.mdpi.com/1422-0067/23/19/11369

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