Effects of gene silencing on cell cycle and apoptosis in the metastatic renal carcinoma cell line ACHN

Objective To explore the role of high mobility group AT-hook 2 (HMGA2) in the regulation of the cell cycle and apoptosis. Methods The renal carcinoma cell line ACHN was transiently transfected with small interfering RNA to knock down the expression of the HMGA2 gene. Cell cycle analysis was undertak...

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Bibliographic Details
Main Authors: Qian Chen, Qizhong Fu, Lin Pu, Xianfeng Liu, Ying Liu
Format: Article
Language:English
Published: SAGE Publishing 2022-02-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605221075511