Adverse clinical outcomes and immunosuppressive microenvironment of RHO-GTPase activation pattern in hepatocellular carcinoma

Adverse clinical outcomes and immunosuppressive microenvironment of RHO-GTPase activation pattern in hepatocellular carcinoma

Abstract Background Emerging evidence suggests that Rho GTPases play a crucial role in tumorigenesis and metastasis, but their involvement in the tumor microenvironment (TME) and prognosis of hepatocellular carcinoma (HCC) is not well understood. Methods We aim to develop a tumor prognosis predictio...

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Bibliographic Details
Main Authors: Qi Yang, Zewei Zhuo, Xinqi Qiu, Ruibang Luo, Kehang Guo, Huihuan Wu, Rui Jiang, Jingwei Li, Qizhou Lian, Pengfei Chen, Weihong Sha, Hao Chen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
Rho GTPases
Hepatocellular carcinoma
Pan-cancer
Immune infiltration
Single-cell transcriptome
Online Access:https://doi.org/10.1186/s12967-024-04926-0

Internet

https://doi.org/10.1186/s12967-024-04926-0

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