Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism

Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism

NONO and SFPQ are involved in multiple nuclear processes (e.g., pre-mRNA splicing, DNA repair, and transcriptional regulation). These proteins, along with NEAT1, enable paraspeckle formation, thus promoting multiple myeloma cell survival. In this paper, we investigate NONO and SFPQ dimer stability,...

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Bibliographic Details
Main Authors: Tommaso Laurenzi, Luca Palazzolo, Elisa Taiana, Simona Saporiti, Omar Ben Mariem, Uliano Guerrini, Antonino Neri, Ivano Eberini
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
DBHS
NONO
SFPQ
structural bioinformatics
Online Access:https://www.mdpi.com/1422-0067/23/14/7626

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https://www.mdpi.com/1422-0067/23/14/7626

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