HOXC13-AS Induced Extracellular Matrix Loss via Targeting miR-497-5p/ADAMTS5 in Intervertebral Disc

HOXC13-AS Induced Extracellular Matrix Loss via Targeting miR-497-5p/ADAMTS5 in Intervertebral Disc

Background/Aims: LncRNAs are a new modulator in the development of intervertebral disc degeneration. However, the functional role and mechanism of HOXC13-AS in intervertebral disc degeneration remain unclear.Methods: qRT-PCR analysis was performed to measure the relative expression levels of HOXC13-...

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Bibliographic Details
Main Authors: Wanli Jing, Wei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
HOXC13-AS
intervertebral disc
miR-497-5p
ADAMTS5
lncRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.643997/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.643997/full

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