Cocaine induces locomotor sensitization through a dopamine-dependent VTA-mPFC-FrA cortico-cortical pathway in male mice

Cocaine induces locomotor sensitization through a dopamine-dependent VTA-mPFC-FrA cortico-cortical pathway in male mice

The prefrontal cortex is involved in cocaine abuse disorders. Here, the authors show that cocaine suppresses frontal association cortex (FrA) in awake mice and induces locomotor sensitization through a dopamine dependent VTA-vmPFC-FrA pathway.

Bibliographic Details
Main Authors: Lun Wang, Min Gao, Qinglong Wang, Liyuan Sun, Muhammad Younus, Sixing Ma, Can Liu, Li Shi, Yang Lu, Bo Zhou, Suhua Sun, Guoqing Chen, Jie Li, Quanfeng Zhang, Feipeng Zhu, Changhe Wang, Zhuan Zhou
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37045-3

Internet

https://doi.org/10.1038/s41467-023-37045-3

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