Role of Pancreatic Stellate Cells in Chemoresistance in Pancreatic Cancer
Pancreatic cancer is highly chemoresistant. A major contributing factor is the characteristic extensive stromal or fibrotic reaction, which comprises up to 90% of the tumour volume. Over the last decade there has been intensive research into the role of the pro-fibrogenic pancreatic stellate cells (...
| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Frontiers Media S.A.
2014-04-01
|
| Серии: | Frontiers in Physiology |
| Предметы: | |
| Online-ссылка: | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00141/full |